Be warned, following these steps WILL void your Xbox 360 warranty. It is therefore advised that you only follow this guide if your console is older than 3 Years.
I have added another guide on DVD drive disassembly for cleaning. Click on my username to find it.
I advise against the use of compressed (canned) air since it tends to just blow dust around rather than fully remove it, however if after brushing the majority of dust away you wish to use it go ahead
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